The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
May. 04, 2012
Herbert Andres, Penzberg, DE;
David Casagolda Vallribera, Penzberg, DE;
Hartmut Duefel, Schlehdorf, DE;
Michael Gerg, Munich, DE;
Christian Scholz, Penzberg, DE;
Michael Schraeml, Penzberg, DE;
Herbert Andres, Penzberg, DE;
David Casagolda Vallribera, Penzberg, DE;
Hartmut Duefel, Schlehdorf, DE;
Michael Gerg, Munich, DE;
Christian Scholz, Penzberg, DE;
Michael Schraeml, Penzberg, DE;
Hoffman-La Roche Inc., Nutley, NJ (US);
Abstract
Herein is reported a fusion polypeptide according to formula (I): NH—S—X—S—COOH, wherein Xcomprises either a random amino acid sequence or an amino acid sequence derived from a first polypeptide, S2 and S1 are non-overlapping amino acid sequences derived from a second polypeptide, and denotes a peptide bond, wherein the second polypeptide is a polypeptide with peptidyl-prolyl cis/trans-isomerase activity (PPIase activity) or is derived from the FKBP-fold domain family, wherein Xis inserted in place of the insert-in-flap-domain of the second polypeptide.