The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Apr. 20, 2011
Applicants:

Oliver Demmer, Munich, DE;

Horst Kessler, Garching, DE;

Hans-jürgen Wester, Ilmmunster, DE;

Margret Schottelius, Munich, DE;

Ingrid Dijkgraaf, Kranenburg, DE;

Andreas Konard Buck, Munich, DE;

Inventors:

Oliver Demmer, Munich, DE;

Horst Kessler, Garching, DE;

Hans-Jürgen Wester, Ilmmunster, DE;

Margret Schottelius, Munich, DE;

Ingrid Dijkgraaf, Kranenburg, DE;

Andreas Konard Buck, Munich, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); C07K 7/64 (2006.01); A61K 51/08 (2006.01);
U.S. Cl.
CPC ...
C07K 7/64 (2013.01); A61K 51/088 (2013.01);
Abstract

The present invention, among others, relates to a compound having a structure according to formula (I) or a pharmaceutically acceptable salt thereof, wherein Xaato Xaaare independently of each other, an optionally N-alkylated natural or unnatural amino acid, R is H or methyl, L is a linker moiety, Ar is a spacer comprising an aromatic moiety, and D comprises, preferably is i) a combination of an organic complexation agent and a detectable label; or ii) a detectable label, an organic complexation agent or an active substance, said active substance particularly being selected from cytotoxic agents, lipids, sugars, sugar conjugates, sugar derivatives, proteins and combinations thereof, with the proviso that -L-Ar-D does not comprise aF-benzoyl residue.


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