The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Oct. 24, 2012
Applicant:

Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing, CN;

Inventors:

Hailin Qin, Beijing, CN;

Wenjie Wang, Beijing, CN;

Zhihui Zhang, Beijing, CN;

Lianqiu Wu, Beijing, CN;

Anjun Deng, Beijing, CN;

Jinqian Yu, Beijing, CN;

Zhihong Li, Beijing, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4741 (2006.01); C07D 491/22 (2006.01); C07D 455/03 (2006.01); C07D 491/04 (2006.01); C07D 491/147 (2006.01);
U.S. Cl.
CPC ...
C07D 491/22 (2013.01); C07D 455/03 (2013.01); C07D 491/04 (2013.01); C07D 491/147 (2013.01);
Abstract

Disclosed are derivatives of protoberberine biological alkaloids or physiologically acceptable salts thereof produced by means of a derivative reaction of a source material of biological alkaline quaternary ammonium salts of protoberberine alkaloids, a preparation method for same and pharmaceutical uses thereof. The derivatives of protoberberine biological alkaloids or the physiologically acceptable salts thereof show activity inhibiting ulcerative colitis and can be used in the preparation of drugs for same.


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