The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Apr. 14, 2015
Applicants:

Jerry Evarts, Seattle, WA (US);

Leena Patel, Mercer Island, WA (US);

Jennifer A. Treiberg, Redmond, WA (US);

Stephane Perreault, Brier, WA (US);

Arthur Yeung, Redmond, WA (US);

Lafe J. Purvis, Ii, Minneapolis, MN (US);

Musong Kim, Bothell, WA (US);

Inventors:

Jerry Evarts, Seattle, WA (US);

Leena Patel, Mercer Island, WA (US);

Jennifer A. Treiberg, Redmond, WA (US);

Stephane Perreault, Brier, WA (US);

Arthur Yeung, Redmond, WA (US);

Lafe J. Purvis, II, Minneapolis, MN (US);

Musong Kim, Bothell, WA (US);

Assignee:

Gilead Calistoga LLC, Foster City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/14 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/08 (2006.01);
U.S. Cl.
CPC ...
C07D 417/14 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 471/08 (2013.01);
Abstract

The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (I), or pharmaceutically acceptable salts thereof, in which R, R, n, R, R, Rand Rare as defined herein. These compounds are useful for treatment of conditions mediated by one or more PI3K isoforms, such as PI3Kδ. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3Kδ.


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