The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
Feb. 15, 2013
Applicants:
University of Cape Town, Rondebosch, ZA;
Mmv Medicines for Malaria Venture, Geneva, CH;
Inventors:
Yassir Younis, Capetown, ZA;
Kelly Chibale, Claremont, ZA;
Michael John Witty, Dover, GB;
David Waterson, Nyon, CH;
Assignees:
MMV MEDICINES FOR MALARIA VENTURE, Geneva, CH;
UNIVERSITY OF CAPE TOWN, Rondebosch, ZA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/4965 (2006.01); C07D 241/20 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 401/10 (2006.01); A61K 31/551 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 241/20 (2013.01); A61K 31/497 (2013.01); A61K 31/4965 (2013.01); A61K 31/5377 (2013.01); A61K 31/551 (2013.01); A61K 45/06 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 401/14 (2013.01); C07D 403/10 (2013.01);
Abstract
The present invention is related to a use of aminopyrazine derivatives in the manufacture of a medicament for preventing or treating malaria. Specifically, the present invention is related to aminopyrazine derivatives useful for the preparation of a pharmaceutical formulation for the inhibition of malaria parasite proliferation. In one embodiment, the invention provides aminopyrazine derivatives having the following formula: