The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
May. 03, 2013
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Lycera Corporation, Ann Arbor, MI (US);
Thomas D. Aicher, Ann Arbor, MI (US);
Kenneth Jay Barr, Boston, MA (US);
Vladimir Simov, South Boston, MA (US);
William D. Thomas, San Jose, CA (US);
Peter L. Toogood, Ann Arbor, MI (US);
Chad A. Van Huis, Hartland, MI (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Lycera Corporation, Ann Arbor, MI (US);
Abstract
The invention provides bicyclic sulfone compounds, pharmaceutical compositions, methods of inhibiting RORy activity, reducing the amount of iL-17 in a subject, and treating immune disorders and inflammatory disorders using such bicyclic sulfone compounds. Another aspect of the invention provides a method of treating a subject suffering from a medical disorder. The method comprises administering to the subject a therapeutically effective amount of one or more bicyclic sulfone compounds described herein. In certain other embodiments, the disorder is rheumatoid arthritis.