The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

Jun. 09, 2014
Applicant:

Nicox S.a., Sophia Antipois-Valbonne, FR;

Inventors:

Nicoletta Almirante, Milan, IT;

Stefano Biondi, Pero, IT;

Ennio Ongini, Segrate, IT;

Laura Storoni, Cesano Maderno, IT;

Alessia Nicotra, Grandate, IT;

Assignee:

Nicox Science Ireland, Dublin, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 291/02 (2006.01); A61K 31/21 (2006.01); C07C 229/20 (2006.01); C07C 203/02 (2006.01); C07C 229/08 (2006.01); C07C 229/22 (2006.01); C07C 229/24 (2006.01); C07C 229/26 (2006.01); C07C 229/36 (2006.01); C07C 237/08 (2006.01); C07C 271/22 (2006.01); C07C 279/14 (2006.01); C07C 323/58 (2006.01); C07D 207/16 (2006.01); C07D 209/52 (2006.01); A61K 31/223 (2006.01); A61K 31/225 (2006.01); A61K 31/265 (2006.01); A61K 31/27 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07C 229/20 (2013.01); A61K 31/223 (2013.01); A61K 31/225 (2013.01); A61K 31/265 (2013.01); A61K 31/27 (2013.01); A61K 31/40 (2013.01); A61K 31/403 (2013.01); A61K 45/06 (2013.01); C07C 203/02 (2013.01); C07C 229/08 (2013.01); C07C 229/22 (2013.01); C07C 229/24 (2013.01); C07C 229/26 (2013.01); C07C 229/36 (2013.01); C07C 237/08 (2013.01); C07C 271/22 (2013.01); C07C 279/14 (2013.01); C07C 291/02 (2013.01); C07C 323/58 (2013.01); C07D 207/16 (2013.01); C07D 209/52 (2013.01);
Abstract

The invention relates to nitric oxide donor compounds and their use for treating cardiovascular diseases, inflammation, pain, fever, gastrointestinal disorders, ophthalmic diseases, hepatic disorders, renal diseases, respiratory disorders, immunological diseases, bone metabolisms dysfunctions, central and peripheral nervous system diseases, sexual dysfunctions, infectious diseases, for the inhibition of platelet aggregation and platelet adhesion, for treating pathological conditions resulting from abnormal cell proliferation, vascular diseases. The invention also relates to compositions comprising at least one nitric oxide releasing compounds of the invention and composition comprising at least one nitric oxide releasing compounds according to the invention and at least one 15 therapeutic agent.


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