The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
Mar. 07, 2014
Applicants:
Michael Anthony James, Big Bend, WI (US);
Haris G. Vikis, Milwaukee, WI (US);
Ming You, Elm Grove, WI (US);
Inventors:
Michael Anthony James, Big Bend, WI (US);
Haris G. Vikis, Milwaukee, WI (US);
Ming You, Elm Grove, WI (US);
Assignee:
The Medical College of Wisconsin, Inc., Milwaukee, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12N 15/1138 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01); C12N 2330/50 (2013.01);
Abstract
Provided herein are compositions for reducing CLPTM1L expression in a cell as well as methods for using such compositions to treat or prevent cancer in a subject. In particular, compositions comprising RNAi-inducing constructs targeted to CLPTM1L and methods of administering such compositions to a subject to treat or prevent a disease or condition associated with CLPTM1L over-expression (e.g., lung cancer) are provided herein.