The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
Dec. 26, 2013
Applicant:
Institute for Cancer Research, Philadelphia, PA (US);
Inventors:
Timothy J. Yen, Haverford, PA (US);
Vikram Bhattacharjee, Philadelphia, PA (US);
Assignee:
Institute for Cancer Research, Philadelphia, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/713 (2006.01); A61K 31/7068 (2006.01); A61K 31/59 (2006.01); C12N 15/113 (2010.01); C12Q 1/68 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 31/59 (2013.01); A61K 31/7068 (2013.01); C12N 15/1138 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01); C12N 2310/531 (2013.01);
Abstract
Methods for treating tumors comprising cells expressing the vitamin D receptor are provided, and comprise inhibiting the expression or the biologic activity of the vitamin D receptor in the tumor cells, and/or inhibiting the expression or the biologic activity of a constituent of the vitamin D receptor signaling pathway in the tumor cells, and administering to the tumor cells an effective amount of gemcitabine.