The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2016
Filed:
Jul. 03, 2008
Shuming Wang, Beijing, CN;
Huiyong Xue, Beijing, CN;
LI Wang, Beijing, CN;
Enhong Zhang, Beijing, CN;
Hongjun Lian, Beijing, CN;
Xiaoyan Shi, Beijing, CN;
Guohua Chi, Beijing, CN;
Yucheng LU, Beijing, CN;
Xiquan Liu, Beijing, CN;
LI Song, Beijing, CN;
Xuying Zhong, Beijing, CN;
Hongguang Du, Beijing, CN;
Shuming Wang, Beijing, CN;
Huiyong Xue, Beijing, CN;
Li Wang, Beijing, CN;
Enhong Zhang, Beijing, CN;
Hongjun Lian, Beijing, CN;
Xiaoyan Shi, Beijing, CN;
Guohua Chi, Beijing, CN;
Yucheng Lu, Beijing, CN;
Xiquan Liu, Beijing, CN;
Li Song, Beijing, CN;
Xuying Zhong, Beijing, CN;
Hongguang Du, Beijing, CN;
Jiangsu Kangbeide Pharmaceuticals Co. Ltd., Nanjing, CN;
Abstract
A Rotigotine-containing composition having a matrix mixture system formed from a polyvinylpyrrolidone and a combination of an acrylic pressure-sensitive adhesive with a silicone pressure-sensitive adhesive. The polyvinylpyrrolidone may be present in an amount of about 1-10% by weight in matrix mixture system. The acrylic pressure-sensitive adhesive may be present in an amount of about 1-25% by weight in the matrix mixture system. The silicone pressure-sensitive adhesive may be present in an amount of about 65-98% by weight in the matrix mixture system. The composition further includes 1-40% of Rotigotine on the basis of the total weight of the composition. The composition provides improved properties in the solubility, release and initial penetration level of Rotigotine. Also disclosed is a transdermal patch that includes the Rotigotine-containing composition, as well as methods of manufacturing and using the Rotigotine-containing composition.