The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2016

Filed:

May. 07, 2008
Applicants:

Raghu Raghavan, Baltimore, MD (US);

Stuart A. Grossman, Towson, MD (US);

Inventors:

Raghu Raghavan, Baltimore, MD (US);

Stuart A. Grossman, Towson, MD (US);

Assignee:

THE JOHNS HOPKINS UNIVERSITY, Baltimore, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 19/00 (2006.01); G06T 7/00 (2006.01); G06F 19/00 (2011.01);
U.S. Cl.
CPC ...
A61B 19/00 (2013.01); G06T 7/0012 (2013.01); A61B 19/50 (2013.01); A61B 2019/501 (2013.01); A61B 2019/562 (2013.01); G06F 19/3437 (2013.01); G06T 2207/30016 (2013.01);
Abstract

Methods and systems for providing planning and dispensation of research and/or treatment for brain disease. Radiological information is generated in a region of interest in an area of the a brain of an individual using a radiological imaging system. A physiological states model is constructed which assesses physiological states of the region of interest. Locations of sources of interstitial fluid flow, fluid conductivities of paths, and anatomical information in the region of interest are obtained using the radiological imaging information. Velocities of the interstitial fluid flow in the region of interest are computed using the physiological states model, the locations of sources of interstitial flow, the fluid conductivities, and the anatomic information. A model of the area of the brain is created, the model including the region of interest.


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