The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2016
Filed:
Jul. 14, 2014
Applicant:
New York University, Brooklyn, NY (US);
Inventors:
Jin Ryoun Kim, Jericho, NY (US);
Michael Hernandez, Ozoner Park, NY (US);
Assignee:
New York University, Brooklyn, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/542 (2006.01); C07K 14/47 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6896 (2013.01); C07K 14/47 (2013.01); G01N 33/542 (2013.01); G01N 2800/2835 (2013.01);
Abstract
A conformation-switching fluorescent protein probe for detection of alpha synuclein oligomers using an alpha synuclein (αS) variant, PG65 (SEQ ID NO: 4), together with a conformation-sensitive fluorescent molecule to create a molecular probe for rapid, specific, and quantitative detection of αS oligomers.