The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2016
Filed:
Oct. 03, 2011
Applicants:
Bianka Prinz, Lebanon, NH (US);
Natarajan Sethuraman, Hanover, NH (US);
Dongxing Zha, Etna, NH (US);
Stefan Wildt, New York, NY (US);
Piotr Bobrowicz, Hanover, NH (US);
Inventors:
Bianka Prinz, Lebanon, NH (US);
Natarajan Sethuraman, Hanover, NH (US);
Dongxing Zha, Etna, NH (US);
Stefan Wildt, New York, NY (US);
Piotr Bobrowicz, Hanover, NH (US);
Assignee:
MERCK SHARP & DOHME CORP., Rahway, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/10 (2006.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1037 (2013.01); C07K 16/2887 (2013.01); C07K 16/32 (2013.01); C12N 15/1034 (2013.01); G01N 33/6854 (2013.01); C07K 2319/30 (2013.01);
Abstract
Methods for display of recombinant whole immunoglobulins or immunoglobulin libraries on the surface of eukaryote host cells, including yeast and filamentous fungi, are described. The methods are useful for screening libraries of recombinant immunoglobulins in eukaryote host cells to identify immunoglobulins that are specific for an antigen of interest.