The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

May. 01, 2013
Applicant:

Eli Lilly and Company, Indianapolis, IN (US);

Inventors:

Gregory Beuerlein, Spring Valley, CA (US);

Julian Davies, La Jolla, CA (US);

Irene Jennifer Denning, San Diego, CA (US);

Ling Liu, Carmel, IN (US);

Jirong Lu, Carmel, IN (US);

Peter Edward Vaillancourt, Del Mar, CA (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); A61K 39/395 (2006.01); G01N 33/574 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/32 (2013.01); C07K 16/2863 (2013.01); G01N 33/5748 (2013.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); G01N 2333/71 (2013.01); G01N 2333/82 (2013.01); G01N 2800/52 (2013.01);
Abstract

The present invention relates to antibodies, or antigen-binding fragments thereof, that bind to the extracellular domain of human c-Met, compositions and kits comprising such c-Met antibodies, or antigen-binding fragments thereof, and methods of using the same for detection of human c-Met that aid in identifying patients with tumors expressing or overexpressing human Met and/or improving their treatment response with anti-c-Met therapeutics.


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