The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Oct. 09, 2009
Applicants:

Kenneth D. Wild, Jr., Simi Valley, CA (US);

James J.s. Treanor, Sherman Oaks, CA (US);

Haichun Huang, Fremont, CA (US);

Heather Inoue, Oak Park, CA (US);

Tie J. Zhang, Thousand Oaks, CA (US);

Frank Martin, Newbury Park, CA (US);

Inventors:

Kenneth D. Wild, Jr., Simi Valley, CA (US);

James J.S. Treanor, Sherman Oaks, CA (US);

Haichun Huang, Fremont, CA (US);

Heather Inoue, Oak Park, CA (US);

Tie J. Zhang, Thousand Oaks, CA (US);

Frank Martin, Newbury Park, CA (US);

Assignees:

Amgen Inc., Thousand Oaks, CA (US);

E. R. Squibb & Sons, L.L.C., Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/00 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); A61K 2039/54 (2013.01); C07K 2317/21 (2013.01); C07K 2317/56 (2013.01); C07K 2317/76 (2013.01);
Abstract

This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of these antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically effective amount of anti-NGF antibodies. Methods of detecting the amount of NGF in a sample using anti-NGF antibodies are also provided.


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