The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Mar. 13, 2009
Applicants:

Peter Kresten Nielsen, Holte, DK;

Frantisek Hubalek, Herlev, DK;

Inger Lautrup-larsen, Virum, DK;

Per Balschmidt, Hørsholm, DK;

Svend Ludvigsen, Lynge, DK;

Thomas Børglum Kjeldsen, Virum, DK;

Inventors:

Peter Kresten Nielsen, Holte, DK;

Frantisek Hubalek, Herlev, DK;

Inger Lautrup-Larsen, Virum, DK;

Per Balschmidt, Hørsholm, DK;

Svend Ludvigsen, Lynge, DK;

Thomas Børglum Kjeldsen, Virum, DK;

Assignee:

Novo Nordisk A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/00 (2006.01); C07K 14/62 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to novel insulin analogs comprising mutations at position A14 in the A chain and at positions B27, B28, B29 and B30 in the B chain and exhibiting resistance towards protease; a method for the preparation of such insulin analogs; insulin preparations containing the insulin analogs of the invention; and, a method of treating diabetes mellitus using these insulin analogs.


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