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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9260494 B1

PDFFull Text
Date of Patent:
Feb. 16, 2016

Filed:

Aug. 09, 2013

Biological active proteins having increased in vivo and/or in vitro stability

Applicant:

Technische Universität München, München, DE;

Inventors:

Arne Skerra, Freising, DE;

Ina Theobald, Landshut, DE;

Martin Schlapschy, Freising, DE;

Assignee:

Technische Universität München, Munich, DE;

Attorney:

Foley & Lardner LLP

Primary Examiner:

Jessica Worsham

Int. Cl.
CPC ...
A61K 38/16 (2006.01); C07K 14/00 (2006.01); C12N 15/63 (2006.01); C12N 5/10 (2006.01); C12P 21/00 (2006.01); C07K 14/47 (2006.01); C07K 14/52 (2006.01); C07K 14/545 (2006.01); C07K 14/56 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/47 (2013.01); C07K 14/52 (2013.01); C07K 14/545 (2013.01); C07K 14/56 (2013.01); A61K 38/00 (2013.01); C07K 2319/35 (2013.01);
Abstract

Increased in vivo and/or in vitro stability is imparted to a biologically active protein by fusing to an amino acid sequence consisting of at least about 100 amino acid residues, which consist essentially of Alanine, Serine and Proline, which form a random coil conformation. Specific examples are described. Also described are related nucleic acids, vectors and cells encoding such amino acids; compositions of biologically active proteins fused to a random coil domain, and methods of making and using the compounds and compositions of the invention.

Find Patent Forward Citations

Skerra, Arne. (2016). Biological active proteins having increased in vivo and/or in vitro stability (U.S. Patent No. 9260494). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9260494

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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