The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2016
Filed:
Nov. 15, 2011
Applicants:
Gabriele Matschiner, Munich, DE;
Andreas Hohlbaum, Paunzhausen, DE;
Kristian Jensen, Landshut, DE;
Inventors:
Assignee:
Pieris AG, Freising-Weihenstephan, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C12N 9/96 (2006.01); C07K 16/44 (2006.01); A61K 38/00 (2006.01); C07K 14/47 (2006.01); C07K 16/00 (2006.01); C12P 21/08 (2006.01);
U.S. Cl.
CPC ...
C07K 14/435 (2013.01); A61K 38/00 (2013.01); C07K 14/47 (2013.01); C07K 14/4725 (2013.01); C07K 16/44 (2013.01); C12N 9/96 (2013.01);
Abstract
Described are specific-binding therapeutic and/or diagnostic proteins directed against Glypican-3 (GPC3), which proteins include muteins of a lipocalin protein, such as lipocalin 2 (Lcn2 or NGAL). The invention also relates to nucleic acid molecules encoding such proteins and to methods for generation and use of such proteins and nucleic acid molecules. Accordingly, the invention also is directed to pharmaceutical and/or diagnostic compositions comprising such lipocalin proteins, including uses of these proteins.