logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9260488 B1

PDFFull Text
Date of Patent:
Feb. 16, 2016

Filed:

Feb. 22, 2013

Replacement therapy for dental caries

Applicants:

Oragenics, Inc., Alachua, FL (US);

The Texas A&m University System, College Station, TX (US);

Inventors:

Jeffrey D. Hillman, Gainesville, FL (US);

James Leif Smith, College Station, TX (US);

Shawanda R. Wilson-Stanford, College Station, TX (US);

Assignees:

Oragenics, Inc., Alachua, FL (US);

Texas A&M University, College Station, TX (US);

Attorney:

McDonnell Boehnen Hulbert & Berghoff LLP

Primary Examiner:

Rodney P Swartz

Int. Cl.
CPC ...
A61K 39/09 (2006.01); A61K 49/00 (2006.01); A61K 39/00 (2006.01); C07K 14/195 (2006.01); C07K 14/315 (2006.01); A23G 4/12 (2006.01); A23L 1/30 (2006.01); A23L 2/52 (2006.01); A61K 8/99 (2006.01); A61K 35/744 (2015.01); A61Q 11/00 (2006.01); C12N 9/04 (2006.01); A01N 25/34 (2006.01); A01N 63/02 (2006.01); A61K 38/16 (2006.01); A61K 45/06 (2006.01); A61K 39/02 (2006.01); A61K 38/12 (2006.01);
U.S. Cl.
CPC ...
C07K 14/195 (2013.01); A01N 25/34 (2013.01); A01N 63/02 (2013.01); A23G 4/123 (2013.01); A23L 1/3014 (2013.01); A23L 2/52 (2013.01); A61K 8/99 (2013.01); A61K 35/744 (2013.01); A61K 38/164 (2013.01); A61K 39/09 (2013.01); A61K 45/06 (2013.01); A61Q 11/00 (2013.01); C07K 14/315 (2013.01); C12N 9/0006 (2013.01); A23V 2002/00 (2013.01); A61K 38/12 (2013.01); A61K 39/02 (2013.01); A61K 2800/74 (2013.01); C12Y 101/01001 (2013.01);
Abstract

The invention provides recombinantstrains that can be used to improve oral health. An embodiment of the invention provides a method of reducing the incidence or severity of dental caries in a dental caries-susceptible host comprising administering orally to the host an isolated recombinantstrain of the invention in an amount effective for replacement of dental caries-causinghost strains in the oral cavity of the host. The isolated recombinantstrain 10 can be contained in a mouthwash, toothpaste, chewing gum, floss, chewable tablet, food, or beverage.

Find Patent Forward Citations

Loading…