The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Jun. 25, 2013
Applicant:

Kyowa Hakko Kirin Co., Ltd., Chiyoda-ku, JP;

Inventors:

Shimpei Yamaguchi, Chiyoda-Ku, JP;

Yumiko Uochi, Chiyoda-Ku, JP;

Tsutomu Agatsuma, Chiyoda-Ku, JP;

Susumu Iwamoto, Chiyoda-Ku, JP;

Hideyuki Onodera, Chiyoda-Ku, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 69/602 (2006.01); C07F 9/141 (2006.01); C07C 69/675 (2006.01); C07C 57/13 (2006.01); C07C 69/708 (2006.01); C07C 235/76 (2006.01); A61K 31/231 (2006.01); C07D 307/33 (2006.01); C12R 1/645 (2006.01); C07C 233/46 (2006.01);
U.S. Cl.
CPC ...
C07F 9/141 (2013.01); A61K 31/231 (2013.01); C07C 57/13 (2013.01); C07C 69/602 (2013.01); C07C 69/675 (2013.01); C07C 69/708 (2013.01); C07C 233/46 (2013.01); C07C 235/76 (2013.01); C07D 307/33 (2013.01); C12R 1/645 (2013.01);
Abstract

A 4,6-hexadecadiene-2,4-dicarboxylic acid derivative represented by the following general formula (1) or a pharmaceutically acceptable salt thereof, each of which has an anti-tumor activity, and the like, are provided. [wherein, Rrepresents hydroxy, —OR(wherein Rrepresents optionally substituted lower alkyl or an optionally substituted aliphatic heterocyclic group), or —NRR(wherein Rand Rmay be the same or different, and each represents a hydrogen atom or optionally substituted lower alkyl) and Rrepresents hydroxy or —OR(wherein Rrepresents optionally substituted lower alkyl or optionally substituted aralkyl)].


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