The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Sep. 26, 2013
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Hyunah Choo, Seoul, KR;

Sun Joon Min, Seoul, KR;

Seon Hee Seo, Seoul, KR;

Jee Yeon Kim, Seoul, KR;

Yoo Ran Ki, Seoul, KR;

Min Joo Kim, Bucheon, KR;

Sora Kim, Incheon, KR;

Youngjae Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); C07D 491/00 (2006.01); C07D 495/00 (2006.01); C07D 495/04 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/519 (2013.01);
Abstract

Disclosed are thienopyrimidinone derivatives as antagonists that act on metabotropic glutamate receptor subtype 1. The thienopyrimidinone derivatives show pharmacological activity against metabotropic glutamate receptor-related diseases, including pain, such as neuropathic pain and migraine, psychiatric diseases, such as anxiety disorder and schizophrenia, urinary incontinence, and neurodegenerative diseases, such as Parkinson's disease and Alzheimer's disease. Also disclosed are methods for preparing the thienopyrimidinone derivatives, and pharmaceutical compositions containing the thienopyrimidinone derivatives as active ingredients.


Find Patent Forward Citations

Loading…