The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Nov. 12, 2014
Applicant:

Theravance Biopharma R&d Ip, Llc, South San Francisco, CA (US);

Inventors:

Robert Murray McKinnell, Millbrae, CA (US);

Daniel D. Long, San Francisco, CA (US);

Lori Jean Van Orden, San Francisco, CA (US);

Lan Jiang, Foster City, CA (US);

Mandy Loo, San Jose, CA (US);

Daisuke Roland Saito, San Mateo, CA (US);

Sheila Zipfel, San Mateo, CA (US);

Eric L. Stangeland, Pacifica, CA (US);

Kassandra Lepack, Calgary, CA;

Gavin Ogawa, San Francisco, CA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); C07D 403/14 (2013.01);
Abstract

The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.


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