The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2016

Filed:

Nov. 08, 2013
Applicant:

Korea Institute of Science and Technology, Seoul, KR;

Inventors:

Kwang Meyung Kim, Seoul, KR;

Ick Chan Kwon, Seoul, KR;

Inchan Youn, Seoul, KR;

Hyun Su Min, Daejeon, KR;

Hong Yeol Yoon, Hwaseong, KR;

Jae Hyung Park, Suwon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/22 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61K 49/223 (2013.01); A61K 49/0032 (2013.01); A61K 49/0069 (2013.01);
Abstract

Disclosed is a liver tumor-targeting ultrasound contrast agent. The ultrasound contrast agent includes a gas-generating core and a hyaluronic acid shell. The ultrasound contrast agent can be specifically delivered to liver cells. This specific delivery enables easy differentiation between normal liver cells and liver tumor cells by ultrasound imaging. In addition, the ultrasound contrast agent is highly stable in aqueous condition and causes no cytotoxicity. Also disclosed is a method for preparing the ultrasound contrast agent.


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