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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9259483 B1

PDFFull Text
Date of Patent:
Feb. 16, 2016

Filed:

Nov. 23, 2012

Peptide sequence design and use thereof for peptide-mediated sirna delivery

Applicants:

Pu Chen, Waterloo, CA;

Mousa Jafari, Waterloo, CA;

Wen Xu, Waterloo, CA;

Baoling Chen, Waterloo, CA;

Ran Pan, Waterloo, CA;

Nedra Karunaratne, Kandy, LK;

Inventors:

Pu Chen, Waterloo, CA;

Mousa Jafari, Waterloo, CA;

Wen Xu, Waterloo, CA;

Baoling Chen, Waterloo, CA;

Ran Pan, Waterloo, CA;

Nedra Karunaratne, Kandy, LK;

Assignee:

Positec Power Tools (Suzhou) Co Ltd, Jiangsu Province, CN;

Attorney:

Dunlap Codding, P.C.

Primary Examiner:

Amy Bowman

Int. Cl.
CPC ...
A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 47/48 (2006.01); A61K 31/713 (2006.01); C12N 15/87 (2006.01); C07K 14/47 (2006.01); C12N 15/11 (2006.01); C07K 19/00 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48323 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/713 (2013.01); C07K 14/4723 (2013.01); C07K 19/00 (2013.01); C12N 15/111 (2013.01); C12N 15/1135 (2013.01); C12N 15/87 (2013.01); A61K 38/00 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01); C12N 2320/51 (2013.01);
Abstract

The invention provides, in one aspect, peptides and a complex comprising one of the peptides and a cargo molecule, wherein the peptide and the cargo molecule are coupled by non-covalently. The peptides of the invention were found to facilitate the delivery of siRNA molecules into cells and to function in siRNA mediated silencing of cellular targets.

Find Patent Forward Citations

Chen, Pu. (2016). Peptide sequence design and use thereof for peptide-mediated sirna delivery (U.S. Patent No. 9259483). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9259483

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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