The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2016
Filed:
Feb. 14, 2014
Applicant:
Alcon Research, Ltd., Fort Worth, TX (US);
Inventors:
Howard Allen Ketelson, Dallas, TX (US);
David L. Meadows, Colleyville, TX (US);
James W. Davis, Suwanee, GA (US);
Assignee:
Alcon Research, Ltd., Fort Worth, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/26 (2006.01); A61K 31/736 (2006.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2006.01); A61K 47/36 (2006.01); A61K 31/08 (2006.01);
U.S. Cl.
CPC ...
A61K 47/26 (2013.01); A61K 9/0048 (2013.01); A61K 31/08 (2013.01); A61K 31/736 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61K 47/36 (2013.01);
Abstract
The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations.