The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

Feb. 24, 2011
Applicants:

Samer Waleed Al-murrani, Topeka, KS (US);

Xiangming Gao, Topeka, KS (US);

Sukhaswami Malladi, Lawrence, KS (US);

Inventors:

Samer Waleed Al-Murrani, Topeka, KS (US);

Xiangming Gao, Topeka, KS (US);

Sukhaswami Malladi, Lawrence, KS (US);

Assignee:

HILL'S PET NUTRITION, INC., Topeka, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/68 (2006.01); A23K 1/18 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A23K 1/1846 (2013.01); G01N 33/6893 (2013.01); C12Q 2600/112 (2013.01); G01N 2800/347 (2013.01);
Abstract

The present invention provides a method of diagnosing the existence of a kidney disorder in a feline comprising measuring the level of expression of one or more biomarkers selected from the group consisting of lumican; collagen alpha 1 (111) chain, variant 12; decorin; secreted frizzled-related protein 2; retinol binding protein 5; MMP-2; MMP-7; and MMP-19, in a biological sample from the feline, wherein differences in expression of the one or more biomarkers in the sample relative to a control value for expression in a sample from a normal animal indicate the existence of a kidney disorder; a method of treating a feline so diagnosed; and compositions, reagents and kits for carrying out the specified methods.


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