The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

Sep. 06, 2010
Applicants:

Richard Anthony Godwin Smith, London, GB;

Steven Howard Sacks, London, GB;

Anthony Dorling, London, GB;

Inventors:

Richard Anthony Godwin Smith, London, GB;

Steven Howard Sacks, London, GB;

Anthony Dorling, London, GB;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/745 (2006.01); C12N 5/071 (2010.01); C12N 9/96 (2006.01); A61K 38/00 (2006.01); C07K 14/81 (2006.01); C07K 14/815 (2006.01);
U.S. Cl.
CPC ...
C12N 9/96 (2013.01); A61K 38/00 (2013.01); C07K 14/811 (2013.01); C07K 14/815 (2013.01); C07K 2319/033 (2013.01);
Abstract

A soluble compound for preventing or reducing blood coagulation comprising an antithrombotic agent and a membrane binding element, wherein the antithrombotic agent has a weight of less than about 5,000 daltons. Also disclosed is a soluble compound for preventing or reducing blood coagulation comprising an anticoagulant joined to a membrane binding element via a joining element, wherein the joining element between the anticoagulant and the membrane binding element is less than about 10,000 daltons in weight. These compounds can be used in therapy and, in particular, in preventing or reducing blood coagulation. As a result, a method of treatment is provided comprising administering an effective amount of the compounds to a subject to prevent or reduce blood coagulation as well as a method of perfusing an organ, tissue or cell comprising contacting the compounds with the organ, tissue or cell to prevent or reduce blood coagulation. Also disclosed is an organ, tissue or cell which has been perfused with the compounds.


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