The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

Feb. 08, 2008
Applicants:

Tomasz Lipinski, Wroclaw, PL;

Andrzej Gamian, Wroclaw, PL;

Ewa Zuziak, Brzeg Dolny, PL;

Agnieszka Korzeniowska-kowal, Miekinia, PL;

Andrzej Gorski, Wroclaw, PL;

Inventors:

Tomasz Lipinski, Wroclaw, PL;

Andrzej Gamian, Wroclaw, PL;

Ewa Zuziak, Brzeg Dolny, PL;

Agnieszka Korzeniowska-Kowal, Miekinia, PL;

Andrzej Gorski, Wroclaw, PL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); C12N 7/02 (2006.01); A61K 35/76 (2015.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/76 (2013.01); C12N 7/02 (2013.01); C12N 2795/00011 (2013.01); C12N 2795/00051 (2013.01); C12N 2795/10132 (2013.01); C12N 2795/10151 (2013.01);
Abstract

A method of preparation of purified bacteriophage with increased antibacterial activity, in which from bacterial lysate of phages is obtained, advantageously in the presence of lysozyme, chelating factor and detergent, in a continuous manner with ultrafiltration on membranes, the phage containing high molecular mass preparation, devoid of bacterial cell wall and other contaminants, free of toxins and endotoxins, active in tests of bacterial lysis, which is characterized by chromatography HPLC, In SDS-PAGE electrophoresis, immunoblotting, biological tests of bacterial lysis, and is dedicated for phage therapy of bacterial infections and tumors and for production of phage deriving pharmaceutical preparations.


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