The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2016
Filed:
Aug. 29, 2013
Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;
Abbvie Inc., North Chicago, IL (US);
Mario Mezler, Forst, DE;
Achim Moeller, Gruenstadt, DE;
Reinhold Mueller, Schifferstadt, DE;
Bernhard K. Mueller, Neustadt, DE;
Tariq Ghayur, Holliston, MA (US);
Eve H. Barlow, Princeton, MA (US);
Martin Schmidt, Bensheim, DE;
Axel Meyer, Schwetzaingen, DE;
Nicole Teusch, Einhausen, DE;
ABBVIE INC., North Chicago, IL (US);
ABBVIE DEUTSCHLAND GMBH & CO. KG, Weisbaden, DE;
Abstract
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind to the Nogo-66 receptor. Specifically, these antibodies have the ability to inhibit the binding of the natural ligand of the Nogo-66 receptor and neutralize the Nogo-66 receptor. These antibodies or portions thereof of the invention are useful for detecting NgR and for inhibiting NgR activity, for example in a human suffering from a disorder in which NgR or Nogo-66 activity is detrimental.