The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2016
Filed:
May. 19, 2014
Applicant:
University of Louisville Research Foundation, Inc., Louisville, KY (US);
Inventor:
Haval Shirwan, Louisville, KY (US);
Assignee:
UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC., Louisville, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); C07K 14/55 (2006.01); A61P 31/00 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01); C07K 14/705 (2006.01); C12N 5/00 (2006.01); C07K 14/36 (2006.01); C07K 14/46 (2006.01); C07K 14/525 (2006.01); A61K 38/00 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C07K 14/55 (2013.01); A61K 38/2013 (2013.01); A61K 39/001 (2013.01); A61K 39/0011 (2013.01); A61K 47/48353 (2013.01); A61K 47/48776 (2013.01); B82Y 5/00 (2013.01); C07K 14/36 (2013.01); C07K 14/46 (2013.01); C07K 14/525 (2013.01); C07K 14/70575 (2013.01); C12N 5/0006 (2013.01); C12N 5/0087 (2013.01); A61K 38/00 (2013.01); A61K 39/00 (2013.01); A61K 2035/122 (2013.01); A61K 2039/5156 (2013.01); C07K 2319/00 (2013.01); Y10S 514/885 (2013.01); Y10S 530/816 (2013.01);
Abstract
Methods and compositions are provided for the persistent modification of cell membranes with exogenous proteins so as to alter the function of the cell to achieve effects similar to those of gene therapy, without the introduction of exogenous DNA. DNA sequences, the proteins and polypeptides embodying these sequences are disclosed for modulating the immune system. The modulations include down-regulation, up-regulation and apoptosis.