The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2016
Filed:
Aug. 10, 2009
Applicants:
John M. Polo, Rancho Santa Fe, CA (US);
Silvia Perri, Castro Valley, CA (US);
Kent Thudium, Oakland, CA (US);
Zequn Tang, San Ramon, CA (US);
Inventors:
John M. Polo, Rancho Santa Fe, CA (US);
Silvia Perri, Castro Valley, CA (US);
Kent Thudium, Oakland, CA (US);
Zequn Tang, San Ramon, CA (US);
Assignee:
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/193 (2006.01); A61K 39/12 (2006.01); C12N 7/01 (2006.01); C12N 15/86 (2006.01); C12N 15/40 (2006.01); C07K 14/005 (2006.01); C12N 7/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 39/12 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/5258 (2013.01); C07K 2319/00 (2013.01); C12N 2740/16222 (2013.01); C12N 2770/36122 (2013.01); C12N 2770/36134 (2013.01); C12N 2770/36143 (2013.01); C12N 2770/36145 (2013.01); C12N 2770/36162 (2013.01); C12N 2810/10 (2013.01);
Abstract
Chimeric alphavirus particles and alphavirus replicon RNAs are provided including methods of making and using same. The alphavirus replicon RNAs comprise deletions in one or more nonstructural proteins. Methods of making, using, and therapeutic preparations containing the chimeric alphavirus particle are disclosed.