IDiyas

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9255107 B1

PDFFull Text
Date of Patent:
Feb. 09, 2016

Filed:

Nov. 27, 2013

Heteroaryl alkyne compound and use thereof

Applicant:

Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, Jiangsu, CN;

Inventors:

Yong Wang, Jiangsu, CN;

Liwen Zhao, Jiangsu, CN;

Di Zhang, Jiangsu, CN;

Feng Wu, Jiangsu, CN;

Sheng Bi, Jiangsu, CN;

Yiping Gao, Jiangsu, CN;

Hongbin Chen, Jiangsu, CN;

Hongyan Chen, Jiangsu, CN;

Cang Zhang, Jiangsu, CN;

Yang Nan, Jiangsu, CN;

Yang Liu, Jiangsu, CN;

Assignee:

NANJING SANHOME PHARMACEUTICAL CO., LTD., Jiangsu, CN;

Attorney:

Oliff PLC

Primary Examiner:

Sun Jae Yoo

Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 233/92 (2006.01); A61K 31/4196 (2006.01); A61K 31/496 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); A61K 31/4985 (2006.01); C07D 233/64 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4178 (2013.01); A61K 31/4196 (2013.01); A61K 31/4439 (2013.01); A61K 31/496 (2013.01); A61K 31/4985 (2013.01); C07D 233/64 (2013.01); C07D 233/92 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01);
Abstract

In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.

Find Patent Forward Citations

Loading…