The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

May. 15, 2013
Applicant:

Chengdu Easton Pharmaceutical Co., Ltd., Chengdu, CN;

Inventors:

Ying Wang, Chengdu, CN;

Yongzhe Xiang, Chengdu, CN;

Guodong Cen, Chengdu, CN;

Long Huang, Chengdu, CN;

Jian Liu, Chengdu, CN;

Ning Zhou, Chengdu, CN;

Jibing Zhang, Chengdu, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/522 (2006.01); C07D 473/08 (2006.01); A61K 31/437 (2006.01); C07D 473/06 (2006.01);
U.S. Cl.
CPC ...
C07D 473/08 (2013.01); A61K 31/437 (2013.01); A61K 31/522 (2013.01); C07D 473/06 (2013.01);
Abstract

The present invention discloses a xanthine derivative having the structure of the following general formula (I) or a pharmaceutically acceptable salt thereof; further discloses a preparation method for the xanthine derivative or a pharmaceutically acceptable salt thereof; and further discloses the use of the xanthine derivative or a pharmaceutically acceptable salt thereof. Through experiments of DPP-IV activity inhibition experiments in vitro, impact on glucose tolerance in normal mice and impact on blood glucose in spontaneous diabetic mice, it proves that the compounds and pharmaceutically acceptable salts thereof show good DPP-IV inhibition activity, can be applied to prepare medicines for treating dipeptidyl peptidase IV-related diseases, and more particularly, can be applied to the use of medicines for treating type II diabetes or diseases of abnormal glucose tolerance.


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