The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

Apr. 16, 2015
Applicants:

Gregory Raymond Bebernitz, Stow, MA (US);

Emma Cody, Cambridge, MA (US);

Tajesh Patel, Medford, MA (US);

Ming Qian, Watertown, MA (US);

Lewis Whitehead, Swampscott, MA (US);

Thomas Zabawa, Boston, MA (US);

Frederic Zecri, Brookline, MA (US);

Inventors:

Gregory Raymond Bebernitz, Stow, MA (US);

Emma Cody, Cambridge, MA (US);

Tajesh Patel, Medford, MA (US);

Ming Qian, Watertown, MA (US);

Lewis Whitehead, Swampscott, MA (US);

Thomas Zabawa, Boston, MA (US);

Frederic Zecri, Brookline, MA (US);

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 405/04 (2006.01); A61K 31/41 (2006.01); C07D 417/12 (2006.01); C07D 405/14 (2006.01); C07D 307/85 (2006.01); A61K 31/343 (2006.01); C07D 407/12 (2006.01); A61K 31/357 (2006.01); A61K 31/443 (2006.01); A61K 31/428 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/343 (2013.01); A61K 31/357 (2013.01); A61K 31/41 (2013.01); A61K 31/428 (2013.01); A61K 31/443 (2013.01); C07D 307/85 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 407/12 (2013.01);
Abstract

The present invention provides a compound of formula I, in which R, R, X and Rare defined in the Summary of the Invention, or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.


Find Patent Forward Citations

Loading…