The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

May. 09, 2013
Applicants:

Joseph T. Bruder, Ijamsville, MD (US);

C. Richter King, New York, NY (US);

Thomas Richie, Glenelg, MD (US);

Keith Limbach, Gaithersburg, MD (US);

Denise Louise Doolan, Camp Hill, AU;

Inventors:

Joseph T. Bruder, Ijamsville, MD (US);

C. Richter King, New York, NY (US);

Thomas Richie, Glenelg, MD (US);

Keith Limbach, Gaithersburg, MD (US);

Denise Louise Doolan, Camp Hill, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/015 (2006.01); C07H 21/04 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/015 (2013.01); C12N 7/00 (2013.01); A61K 2039/53 (2013.01); C12N 2710/10043 (2013.01);
Abstract

The invention provides a method of inducing an immune response against malaria in a mammal. The method comprises intramuscularly administering to a mammal a composition comprising a pharmaceutically acceptable carrier and either or both of (a) a first adenoviral vector comprising a nucleic acid sequence encoding acircumsporozoite protein (CSP) operably linked to a human CMV promoter, and/or (b) a second adenoviral vector comprising a nucleic acid sequence encoding aapical membrane antigen 1 (AMA-1) antigen operably linked to a human CMV promoter.


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