The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2016

Filed:

Jun. 15, 2007
Applicants:

George Cotsarelis, Berwyn, PA (US);

Luis Garza, Baltimore, MD (US);

Inventors:

George Cotsarelis, Berwyn, PA (US);

Luis Garza, Baltimore, MD (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/557 (2006.01); A61K 8/36 (2006.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); A61Q 7/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/557 (2013.01); A61K 8/36 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61Q 7/00 (2013.01);
Abstract

This invention provides methods of treating androgenetic alopecia (AGA), acne, rosacea, prostate cancer, and benign prostatic hypertrophy (BPH), comprising the step of contacting a subject with a compound or composition capable of decreasing prostaglandin D2 (PGD2) level or activity, a downstream signaling or receptor pathway thereof, or prostaglandin D2 synthase level or activity; methods of stimulating hair growth, comprising the step of contacting a subject with a compound or composition capable of increasing or decreasing the activity or level of a target gene of the present invention, or with a protein product of the target gene or an analog or mimetic thereof; and methods of testing for AGA and evaluating therapeutic methods thereof, comprising measuring PGD2 levels.


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