The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2016
Filed:
May. 14, 2009
Applicants:
Andrew Lennard Lewis, Farnham, GB;
Giuseppe Battaglia, Sheffield, GB;
Irene Canton, Sheffield, GB;
Peter William Stratford, Farnham, GB;
Inventors:
Andrew Lennard Lewis, Farnham, GB;
Giuseppe Battaglia, Sheffield, GB;
Irene Canton, Sheffield, GB;
Peter William Stratford, Farnham, GB;
Assignee:
BIOCOMPATIBLES UK LIMITED, Farnham Surrey, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/00 (2006.01); C12N 5/071 (2010.01); A61K 31/7105 (2006.01); B82Y 5/00 (2011.01); A61K 9/127 (2006.01); A61K 48/00 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 9/0019 (2013.01); A61K 9/1273 (2013.01); A61K 48/0041 (2013.01); C12N 15/111 (2013.01); C12N 2320/32 (2013.01);
Abstract
The present invention provides a composition comprising vesicles and encapsulated within the vesicles, nucleic acid comprising less than 1000 nucleotides, wherein the vesicles comprise an amphiphilic block copolymer having a hydrophilic and a hydrophobic block. Methods of forming vesicles and methods of delivering nucleic acid, in particular, iRNA into cells, are also provided.