The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jun. 29, 2012
Brian Christopher Bales, Niskayuna, NY (US);
Brian James Grimmond, Clifton Park, NY (US);
Daniel Eugene Meyer, Clifton Park, NY (US);
Bruce Allan Hay, Niskayuna, NY (US);
Michael Todd Luttrell, Canton, MI (US);
Brian Christopher Bales, Niskayuna, NY (US);
Brian James Grimmond, Clifton Park, NY (US);
Daniel Eugene Meyer, Clifton Park, NY (US);
Bruce Allan Hay, Niskayuna, NY (US);
Michael Todd Luttrell, Canton, MI (US);
General Electric Company, Niskayuna, NY (US);
Abstract
A method of sterilizing a nanoparticle preparation at a high temperature is provided. A plurality of nanoparticles are purified to form the preparation, wherein the nanoparticles comprise at least a core and a shell and the shell comprises one or more ligand species attached to the core. The nanoparticle preparation is made by a purified nanoparticle composition, a carrier fluid and an excess of the one or more ligand species not attached to the core. The ligand species attached to the core and the excess ligand species added after purification are structurally identical. The nanoparticle preparation provided by the present invention may be used as contrast agents in medical imaging techniques such as X-ray and magnetic resonance imaging.