The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9250252 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 02, 2016

Filed:

May. 29, 2009
Applicants:

Yamuna Krishnan, Bangalore, IN;

Satyajit Mayor, Bangalore, IN;

Souvik Modi, Bangalore, IN;

Inventors:

Yamuna Krishnan, Bangalore, IN;

Satyajit Mayor, Bangalore, IN;

Souvik Modi, Bangalore, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/84 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
G01N 33/84 (2013.01); A01K 2207/05 (2013.01); A01K 2227/703 (2013.01); A01K 2267/0393 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6876 (2013.01);
Abstract

Disclosed are nucleic acid-based sensors for measuring the pH of a sample, including cells, regions thereof, and whole organisms. The sensor includes an I-switch that is triggered by protons, and which functions as a FRET-based pH sensor inside living cells and organisms. Also disclosed are compositions and methods for measuring the pH of a specific region of a cell, such as vesicles, the nucleus, mitochondrial matrix, or the Golgi lumen.


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Krishnan, Yamuna. (2016). Intracellular ph sensor using nucleic acid assemblies (U.S. Patent No. 9250252). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9250252

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