The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Sep. 14, 2009
Wayne Forrest Patton, Dix Hills, NY (US);
Jack Coleman, East Northport, NY (US);
Yuejun Xiang, Bayside, NY (US);
Praveen Pande, Holbrook, NY (US);
Zaiguo LI, Fresh Meadows, NY (US);
Wayne Forrest Patton, Dix Hills, NY (US);
Jack Coleman, East Northport, NY (US);
Yuejun Xiang, Bayside, NY (US);
Praveen Pande, Holbrook, NY (US);
Zaiguo Li, Fresh Meadows, NY (US);
Enzo Biochem, Inc., Farmingdale, NY (US);
Abstract
Provided are assays useful for detecting and monitoring autophagy and phospholipidosis, including the progression of lysosomal storage diseases. Drugs and treatments for lysosomal storage diseases can be monitored for effectiveness in lysosomal storage disease conditions. Drug candidates and suspected toxic agents can also be screened for toxicity to cells, tissues and organs. Also provided are methods for distinguishing between phospholipidosis activators and autophagy pathway perturbation agents.