The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Dec. 29, 2011
Michael P. Caulfield, San Clemente, CA (US);
Jackie Liu, Tustin, CA (US);
Dawn Shalhout, Trabuco Canyon, CA (US);
Zhihong Chen, Aliso Viejo, CA (US);
Michael P. Caulfield, San Clemente, CA (US);
Jackie Liu, Tustin, CA (US);
Dawn Shalhout, Trabuco Canyon, CA (US);
Zhihong Chen, Aliso Viejo, CA (US);
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED, Wilmington, DE (US);
Abstract
The invention provides apparatus and methods of preparation of lipoproteins from a biological sample, including HDL, LDL, Lp(a), IDL, and VLDL, for diagnostic purposes utilizing differential charged-particle mobility analysis methods. Further provided are methods for analyzing the size distribution of lipoproteins by differential charged-particle mobility, which lipoproteins are prepared by methods of the invention. Further provided are methods for assessing lipid-related health risk, cardiovascular condition, risk of cardiovascular disease, and responsiveness to a therapeutic intervention, which methods utilize lipoprotein size distributions determined by methods of the invention.