The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Jun. 17, 2011
Applicants:

Anna Scherzinger, Bernried, DE;

Sonja Molinaro, Weilheim, DE;

Bernd Buchberger, Zeitlarn/Laub, DE;

Inventors:

Anna Scherzinger, Bernried, DE;

Sonja Molinaro, Weilheim, DE;

Bernd Buchberger, Zeitlarn/Laub, DE;

Assignee:

HYGLOS INVEST GMBH, Bernried, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/08 (2006.01); C12Q 1/18 (2006.01); C12N 15/62 (2006.01); C12Q 1/37 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/18 (2013.01); C12N 15/62 (2013.01); C12Q 1/37 (2013.01); G01N 33/6845 (2013.01); C07K 2319/00 (2013.01); C40B 30/08 (2013.01); G01N 2333/4722 (2013.01); G01N 2333/952 (2013.01);
Abstract

The present invention relates to novel methods of generating and screening for chimeric polypeptides, which can be used in the treatment and prophylaxis of pathogenic bacterial contamination, colonization and infection. The novel methods are based on random recombination of protein domains, and the chimeric polypeptides obtainable by the methods according to the invention are characterized in that they comprise at least one enzymatic active domain (EAD) and at least one cell binding domain (CBD). The present invention also relates to a library of chimeric polypeptides obtainable by the methods of the present invention.


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