The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Sep. 28, 2012
Anais Girard-gagnepain, Lyons, FR;
Els Verhoeyen, Lyons, FR;
Dimitri Lavillette, Lyons, FR;
Francois-loic Cosset, Lyons, FR;
Anais Girard-Gagnepain, Lyons, FR;
Els Verhoeyen, Lyons, FR;
Dimitri Lavillette, Lyons, FR;
Francois-Loic Cosset, Lyons, FR;
Institut National de la Sante et de la Recherche Medicale (INSERM), Paris, FR;
Ecole Normale Superieur de Lyon, Lyons, FR;
Abstract
The present invention concerns a pseudotyped viral vector particle for transferring biological material into cells, wherein said vector particle comprises at least:—a chimeric envelope glycoprotein which comprises or consists in a fusion of the transmembrane and extracellular domain of a baboon endogenous retrovirus (BaEV) envelope glycoprotein and the cytoplasmic tail domain of a murine leukemia virus (MLV) envelope glycoprotein; or—a modified BaEV envelope glycoprotein wherein the cytoplasmic tail domain is devoid of the fusion inhibitory R peptide.