The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Apr. 29, 2015
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Kevin Fitzgerald, Brookline, MA (US);
James Butler, Lynnfield, MA (US);
Brian Bettencourt, Groton, MA (US);
Anna Borodovsky, Melrose, MA (US);
Satyanarayana Kuchimanchi, Acton, MA (US);
Klaus Charisse, Acton, MA (US);
Muthiah Manoharan, Weston, MA (US);
Martin Maier, Belmont, MA (US);
Kallanthottathil G. Rajeev, Wayland, MA (US);
Donald Foster, Attleboro, MA (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria.