The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
May. 30, 2006
Stefan Schulte, Marburg, DE;
Hans-peter Hauser, Marburg, DE;
Uwe Kalina, Marburg, DE;
Thomas Weimer, Gladenbach, DE;
Stefan Schulte, Marburg, DE;
Hans-Peter Hauser, Marburg, DE;
Uwe Kalina, Marburg, DE;
Thomas Weimer, Gladenbach, DE;
CSL Behring GmbH, Marburg, DE;
Abstract
The present invention relates to modified cDNA sequences coding for human Factor X and their derivatives with improved stability and modified activation sequences, recombinant expression vectors containing such cDNA sequences, and host cells transformed with such recombinant expression vectors. The invention also relates to recombinant factor X polypeptides and derivatives which have biological activities of the unmodified wild type protein but with improved stability and processes for the manufacture of such recombinant proteins and their derivatives. The invention also covers a transfer vector for use in human gene therapy, which comprises such modified DNA.