The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Apr. 23, 2007
Applicants:

Jeffery M. Gimble, Baton Rouge, LA (US);

John W. Ludlow, Carrboro, NC (US);

Inventors:

Jeffery M. Gimble, Baton Rouge, LA (US);

John W. Ludlow, Carrboro, NC (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0672 (2013.01); C12N 5/067 (2013.01); C12N 2500/30 (2013.01); C12N 2500/38 (2013.01); C12N 2500/42 (2013.01); C12N 2500/62 (2013.01); C12N 2500/90 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/12 (2013.01); C12N 2501/23 (2013.01); C12N 2501/237 (2013.01); C12N 2506/1384 (2013.01);
Abstract

The present invention provides a method to derive hepatic stem cells from stem cells derived from non-liver tissue. In one embodiment of the invention, hepatic stem cells are derived from adipose stem cells. The invention also provides a method of enhancing hepatic cytokine production (e.g., HGF) from ASCs, which may be useful in the regeneration of liver tissue when transplanted in vivo. Tissue culture conditions, including media conditions, are provided.


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