The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2016

Filed:

Jan. 29, 2014
Applicants:

The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);

The Massachusetts Institute of Technology, Cambridge, MA (US);

Inventors:

Joseph Cuiffi, Fort Myers, FL (US);

Mark Joseph Mescher, West Newton, MA (US);

Jonathan Robert Coppeta, Windham, NH (US);

Samuel Walker Inman, Boston, MA (US);

Abigail June Spencer, Boston, MA (US);

Transon Van Nguyen, San Diego, CA (US);

Jeffrey T. Borenstein, Newton, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/00 (2006.01); C12N 5/071 (2010.01); C12M 1/32 (2006.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0602 (2013.01); C12M 21/08 (2013.01); C12M 23/12 (2013.01); C12M 23/44 (2013.01); C12M 29/00 (2013.01); C12M 29/12 (2013.01); C12M 41/00 (2013.01);
Abstract

The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the organ systems are fluidically connected with a constant-volume pump.


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