The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jun. 22, 2012
Bruno Robert, Montpellier, FR;
Benedicte Fauvel, Montpellier, FR;
Gwenael Cheve, Montpellier, FR;
Aziz Yasri, Montpellier, FR;
Christel Larbouret, Montpellier, FR;
Wilhem Leconet, Montpellier, FR;
Thierry Chardes, Montpellier, FR;
Christian Larroque, Montpellier, FR;
Andre Pelegrin, Montpellier, FR;
Bruno Robert, Montpellier, FR;
Benedicte Fauvel, Montpellier, FR;
Gwenael Cheve, Montpellier, FR;
Aziz Yasri, Montpellier, FR;
Christel Larbouret, Montpellier, FR;
Wilhem Leconet, Montpellier, FR;
Thierry Chardes, Montpellier, FR;
Christian Larroque, Montpellier, FR;
Andre Pelegrin, Montpellier, FR;
ORIBASE PHARMA, Montpellier Cedex, FR;
Institut Regional du Cancer de Montpellier-Val d' Aurelle, Montpellier Cedex, FR;
INSERM (Institut National de la Sante et de la Recherche Medicale), Paris, FR;
UNIVERSITE DE MONTPELLIER 1, Montpellier Cedex, FR;
Abstract
The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9, SEQ ID NO: 10 and SEQ ID NO: 11.