The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Jan. 26, 2010
Florence Dal Degan, Virum, DK;
Mark J. Newman, Duluth, GA (US);
Jeffery L. Alexander, San Diego, CA (US);
Scott Southwood, Santee, CA (US);
Florence Dal Degan, Virum, DK;
Mark J. Newman, Duluth, GA (US);
Jeffery L. Alexander, San Diego, CA (US);
Scott Southwood, Santee, CA (US);
Epimmune Inc., San Diego, CA (US);
Abstract
The present invention provides novel artificial oligopeptides capable of binding HLA Class II molecules encoded by several alleles. The oligopeptides include the sequence AXFVAAXTLXAXA (SEQ ID NO:1), wherein Xis selected from the group consisting of W, F, Y, H, D, E, N, Q, I and K; Xis selected from the group consisting of F, N, Y and W; Xis selected from the group consisting of H and K, and Xis selected from the group consisting of A, D and E, with the proviso that the oligopeptide sequence is not AKFVAAWTLKAAA. The invention also relates to larger peptides comprising the oligopeptides, polynucleotides encoding the oligopeptides and larger peptides, as well as to compositions comprising the oligopeptides, peptides or polynucleotides. Also disclosed are methods for inducing immune responses.