The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2016
Filed:
Feb. 21, 2014
Bristol-myers Squibb Company, Princeton, NJ (US);
Jacob Swidorski, Southington, CT (US);
Yan Chen, Wallingford, CT (US);
Sing-Yuen Sit, Meriden, CT (US);
Nicholas A. Meanwell, East Hampton, CT (US);
Alicia Regueiro-Ren, Middletown, CT (US);
Jie Chen, Madison, CT (US);
Zheng Liu, Beacon Falls, CT (US);
Richard A. Hartz, Middletown, CT (US);
Li Xu, Middletown, CT (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, alkyl and alkenyl C-3 modified betulinic acid derivatives that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV: a compound of Formula I The compounds are useful for the treatment of HIV and AIDS.